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ZenZema Eczema Itch Spray

Our proprietary Ecz-Rx formula targets the source for powerful, lasting relief.

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HSA/FSA Eligible

Details

When flares cause itch, calm your skin and find relief with Eczema Itch Spray. Our proprietary Ecz-Rx® formula targets the source for powerful, lasting relief.

How to use

Apply twice daily to clean, dry skin. Allow to air dry before applying other products or moisturizers.

Ingredients

Active Ingredient: Colloidal Oatmeal 0.01% (skin protectant). Inactive Ingredients: Water (Aqua), Sodium Chloride, Benzyl Alcohol, Phenoxyethanol, Hydroxyethylpiperazine Ethane Sulfonic Acid, EczRx, Sodium Hydroxide

Powered by Ecz-Rx

Our precision formula is designed to work fast and deliver long-lasting itch relief while helping balance the skin’s microbiome.

  • Targets Root Cause

  • Balances Microbiome

How it works

ZenZema® FAQs

What is ZenZema?

ZenZema is a science-first skin care brand formulated exclusively for eczema-prone (atopic dermatitis–prone) skin. Our products help relieve itch, protect dry and irritated skin, and support both the skin barrier and microbiome balance - so skin can feel calmer, more comfortable, and more resilient.

Is ZenZema safe for sensitive skin?

Yes. All ZenZema topical products are formulated for skin sensitivities associated with eczema-prone and atopic dermatitis-prone skin. They are dermatologist approved, National Eczema Association Seal Accepted, MyMicrobiome Certified, and tested extensively on sensitive skin. They are steroid, fragrance, antibiotic, paraben, and sulphate free.

How fast will I feel itch relief with the ZenZema Eczema Itch Spray?

Many individuals experience soothing hydration quickly after application. In ZenZema Eczema Itch Spray studies, 89% of users reported itch relief within the first 12 hours. Unlike some treatments that may initially cause irritation, this product typically provides immediate comfort, lasting relief, and steady improvement. Many individuals experience improved sleep, gaining itch relief through the night.

What ages can use ZenZema?

ZenZema Eczema Itch Spray is tested and safe for use for adults and children 3 months and older.

Can I use ZenZema with other eczema treatments?

ZenZema products are designed to be easily incorporated into eczema and atopic dermatitis care routines including moisturizers, steroid creams, and prescription treatments. Consult your healthcare provider for personalized guidance, especially for infants or severe cases.

Reviews

  • 5 stars: 17 (85%)
  • 4 stars: 1 (5%)
  • 3 stars: 1 (5%)
  • 2 stars: 0 (0%)
  • 1 star: 1 (5%)
K
Kyle

My son has had incredibly itchy eczema on the back of his legs and his arms most of his life. With this product, his arms are completely clear and his legs just keep getting better every day, especially the itching on the back of the legs. This product has been a lifesaver..

L
Lelajudesch

Ich habe das ZenZema-Spray zu meiner großen Freude zum testen erhalten. Innerhalb kürzester Zeit habe ich eine deutliche Verbesserung meiner Psoriasis feststellen können.
Leider ist das Spray in Deutschland noch nicht erhältlich und die Flasche relativ klein, was bei einem stärkeren Befall der Haut -wie bei mir- keine allzu lange Testzeit zugelassen hat.
Was ich jedoch in dieser kurzen Zeitspanne erreichen konnte, ohne Kortison, ist phantastisch!
Ich würde mich sehr freuen, wenn es das Spray auch demnächst hier zu kaufen gibt.

O
Ostertag

More photos

O
Ostertag

My wife suffered from severe Eczema on her hands. She would not join social events and experienced pain when using her hands.
No therapy worked. We tested ZenZema and within the first day the pain and itching was reduced. Within ten days the skin repaired itself. My wife is 78 years old and we are more than grateful for this great product. My name is Ostertag and you can use my name as reference.

Thank you so much, Ostertag, for sharing your inspiring story! We're thrilled to hear about your wife's improvement and that ZenZema could help. Wishing her continued comfort and health!

A
Aidan

I have been using the product for about 9 days now and have seen tremendous results just in the one area I am spraying!

I have been living with atopic dermatitis for all of my life and tried every OTC product and prescription steroids creams you can think of and none has worked this fast and shown me results and relief like ZenZema’s eczema itch spray has in such a short amount of time.

I purposely have been using it on one area to compare how my other areas have been looking compared to the spot I have been using it on and the difference is night and day!

Hi there! We're thrilled to hear how well ZenZema's Eczema Itch Spray is working for you. Thank you for sharing your experience, and we're so glad it brings you relief. Wishing you many more itch-free days ahead!

A
Anonymous

I started using this product to help with itch and what was very helpful is I could apply the spray which gave me immediate relief and then apply my my eczema lotion, which was always very itchy for the first 10 minutes or so. Using both now my eczema heals much quicker. I really do appreciate the product.

Hi there! We're thrilled to hear that our ZenZema Eczema Itch Spray provides you with quick relief and helps your eczema heal faster. We truly appreciate your support!

A
Anonymous

Excellent experience and very elegant and effective product

We're thrilled to hear that your patients are having an excellent experience with our ZenZema Eczema Itch Spray. We are excited to bring this new technology to those suffering with eczema, and your feedback is so important!

A
Anonymous

Patient reports itch relief but only temporary. It is a good option for patient to choose non steroidal treatment to manage itching

Thank you for sharing your patient's experience! Please encourage your patients to use twice daily for lasting relief. Unlike steroidal treatments, ZenZema guarantees, lasting eczema itch control without the tradeoffs.

A
Anonymous

Like the unique spray formulation of colloidal oatmeal. ,soothing can
use all year round nonsticky for hot summer , calming effect for skin irritation

Thank you for sharing your experience! We're glad you find the spray soothing and we appreciate the feedback on our lightweight formula. Wishing you many itch-free days!

L
Lexi Anderson

We’ve been using ZenZema on my son’s eczema for about five days, and it really seems to be helping with the itching. He’s scratching much less, and his skin is finally starting to heal. Easy to apply and definitely worth trying!

Hi Lexi, we're so happy to hear that ZenZema is helping your son! Thank you for sharing his story with us.

A
Anonymous

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D
Daniel Manrique

Sorry, but I do not never received any product

Dr. Manrique, we are so sorry you didn't receive the product we shipped to you. Delivery was attempted July 2 and then the product was returned to our warehouse. Please email us at hcp.zenzema.com if there are special delivery instructions for your office.

B
Barbara Hisler

Patients say it works well!

Thank you, Dr, Hisler! We're so glad to hear that patients are finding it effective. We appreciate your support!

N
Nyshia Garcia

Small travel size that works well!

Hi there! We're so pleased to hear that ZenZema is working for you! Thanks for your sharing your experience.

K
Kim Heston

Effective, fast relief!

Hi Kim, we're thrilled to hear that the ZenZema Eczema Itch Spray provided you with fast relief! Thank you for sharing your experience.

A
Alex Farkouh

Immediately got rid of my itchy skin!

Hi Alex, we're thrilled to hear the ZenZema Eczema Itch Spray helped soothe your skin! Thanks for sharing your experience.

S
Steph Schilling

Does relieve itch, but for a short amount of time. The application spray is too heavy- it drips a lot and I have to rub it in

Hi Steph, thank you for sharing your feedback. We’re glad the spray helped with your eczema itch, and we’ll look into making the application easier to use. A little goes a long way! Your input is appreciated!

T
Tom Browning

ZenZema has been a great find for our family. It provides powerful, lasting itch relief without steroids, which gives me real peace of mind. I also appreciate that it is thoughtfully designed for eczema-prone skin and focused on helping restore balance at the microbiome level.

Most importantly, ZenZema provided quick relief for my son Joey when he really needed it. Seeing him feel more comfortable so quickly made a big difference. I’m very grateful to have found a product that feels gentle, effective, and made with real care.

Hi Tom, thank you so much for sharing your experience! We're delighted to hear that ZenZema has brought relief and comfort to your family. Your kind words truly mean a lot to us. Wishing Joey continued itch-free days and nights!

A
Anonymous

I’ve been struggling with eczema on my face on and off for a few years now. I’ve tried other forms of treatment and none of them have worked. After using this product for just a few days, I noticed a drastic change, and after two months, it was completely gone. Clear skin, and zero itchiness! This product is incredible, I will always have it on hand just in case!

Hi there! We're thrilled to hear about your fantastic results with our ZenZema Eczema Itch Spray. Thank you for sharing your experience and for trusting our product. Wishing you continued skin health!

E
Erika

I have been suffering with extreme eczema for months on my ankles and legs - have tried every prescription and OTC topical. The itching has been unbearable and my legs are a mess. Then enter ZenZema! It saved me. My ankles and legs responded immediately - the temptation to scratch diminished and my skin looks so so much better! Thank you ZenZema for improving my life - I can confidently wear sundresses again!

Hi there, thank you so much for sharing your wonderful experience! We're thrilled to hear that ZenZema has made such a positive impact on your skin and confidence. Wishing you continued comfort!