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Certified Microbiome Friendly for Eczema
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Accepted by the National Eczema Association
The power of your microbiome
Powerful, lasting itch relief. Steroid-free formulations. Precision-designed for eczema-prone skin.
Balance at the microbiome level.
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SHOP Eczema Itch SprayPowerful, lasting itch relief.
ZenZema® Eczema Itch Spray is precision-designed for eczema-prone skin. It is non-irritating, and can be easily added to any eczema treatment plan.
Real proof. Real results. Calmer skin you can see and feel.
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Target area - Under Arm
ZenZema Eczema Itch Spray
Before - Day 1, After - Day 10
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Target area - Hands
ZenZema Eczema Itch Spray
Before - Day 1, After - Day 16
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Target area - Arms
ZenZema Eczema Itch Spray
Before - Day 1, After - Day 10
Breaking Down the Cycle from Flare to Relief
Step 0 A Healthy Microbiome
Your skin is more than a surface, it’s a living shield. At the top layer sits a delicate ecosystem called the skin microbiome. It’s a diverse community of microorganisms that help defend, protect, and maintain moisture.
When this microbiome is balanced, skin stays strong, resilient, and calm.
Step 1 The skin microbiome gets out of balance
But atopic dermatitis or eczema-prone skin is often linked to an imbalance in the microbiome – sometimes even before irritation appears. This imbalance is considered the root cause of itchy flares.
As harmful bacteria multiply the beneficial bacteria become outnumbered. This results in a weakened, dry and compromised skin barrier. Skin becomes stressed – and more vulnerable.
Step 2 Irritants can trigger itch and discomfort
When the microbiome is out of balance, certain bacteria release enzymes that irritate the skin and activate itch-sensing nerve endings.
That “can’t ignore it” itch begins and visible redness and irritation appear.
Scratching only further disrupts the barrier, increasing irritation, triggering more itch, and creating an unbearable cycle.
Over time, skin feels increasingly reactive and the cycle continues.
Step 3 Restoring balance
Restoring a healthy microbiome is essential to calming eczema-prone skin.
ZenZema® Eczema Itch Spray helps rebalance the skin’s microbiome and strengthen the barrier.
So you can break the cycle and find relief.
Step 4 Relief at last
With the microbiome supported and the barrier restored, skin feels calmer and more comfortable.
Itch episodes are reduced. Flare-ups become less intense.
This is the calm eczema-prone skin has been waiting for.
ZenZema® It’s Relief. At Last.
Our Scientific Advisory Board
Where breakthrough science begins.
ZenZema® formulas have been rigorously developed alongside leading dermatologists and itch researchers to ensure precision, safety and efficacy.
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Dr. Gil Yosipovitch
Leading Eczema/Itch Dermatologist -
Dr. Amy Paller
Leading Pediatric Dermatologist with 100+ Clinical Trials -
Dr. Francis McGlone
PhD in Skin Sensation & Itch -
Dr. Irena Pastar
Skin Microbiome PhD -
Dr. Isaac Chiu
Harvard PhD Immunologist
& Microbiome Expert
