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ZenZema
Eczema Itch Spray

The first endolysin spray formulated specifically for patients living with atopic dermatitis.

  • Targets Root Cause

  • Long-Lasting Itch Relief

  • Balances Microbiome

  • Fast Acting

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Addressing the Root Cause of Eczema-Related Itch

In the US alone, 31 million people are living with atopic dermatitis, including 13% of all children. With the itch associated with eczema causing both a physical and emotional hardship, we understand your patients are looking for answers.

At ZenZema we are committed to developing solutions specifically for your atopic patients. Our ZenZema Eczema Itch Spray, with our Ecz-Rx technology, specifically addresses the microbiome dysbiosis that drives eczema flares and associated pruritus.

Powered by Ecz-Rx

ZenZema Eczema Itch Spray features our patented Ecz-Rx technology, a precision enzyme technology developed specifically for eczema-prone skin and to address microbiome imbalance and the troubling symptoms it can cause.

After evaluating hundreds of enzyme candidates, Ecz-Rx® was selected for its precision efficacy, gentleness, and real-world formulation stability. It remains stable across typical temperatures and pH conditions and is designed for everyday use without refrigeration.

To learn more or to explore the science. Contact us at: hcp@zenzema.com.

ZenZema® FAQs

What is ZenZema?

ZenZema is a science-first skin care brand formulated exclusively for eczema-prone (atopic dermatitis–prone) skin.

Our products help relieve itch, protect dry and irritated skin, and support both the skin barrier and microbiome balance - so skin can feel calmer, more comfortable, and more resilient.

How is ZenZema different from other eczema brands?

Eczema is a complex inflammatory skin condition with a variety of causes and triggers that are unique to patients living with AD.

While other brands focus on sensitive skin and rely heavily on the benefits of colloidal oatmeal and barrier lipids, ZenZema specializes in ONLY eczema care with unique combinations of advanced precision ingredients for a more comprehensive approach.

Our microbiome-conscious formulation prioritizes gentleness, long-term stability, and above all, lasting relief.

What is the skin microbiome and why is it important for eczema?

The skin is home to about a thousand different types of bacteria. When our skin is healthy, there is a perfect balance of good bacteria.

When eczema flares, the bad bacteria become more dominant and can damage the skin barrier, drive troublesome itch, redness, and excessive dryness.

Restoring balance to the skin microbiome is essential in eczema care.

How does ZenZema support the skin microbiome?

Eczema-prone/atopic dermatitis-prone skin is often associated with barrier disruption and microbial imbalance.

ZenZema formulations are designed to support barrier function while maintaining a balanced microbial environment on the skin.

All topical ZenZema products are MyMicrobiome certified.

Will ZenZema cure eczema/atopic dermatitis?

There is currently no cure for eczema or atopic dermatitis. ZenZema products are designed to help relieve itch and protect dry, irritated skin as part of a comprehensive eczema management routine.

When used as directed, individuals have experienced significant relief from itch and seen visible results.